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HelpOrderable Name TAPNS Tapentadol and Metabolite, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.0 mL Serum
Collection Instructions: Within 2 hours of collection, centrifuge and aliquot serum into a plastic vial.
Useful For
Monitoring medication compliance in patients who are prescribed tapentadol
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Specimen Type
Serum RedSpecimen Minimum Volume
Serum: 0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 14 days |
| Frozen | 28 days | |
| Ambient | 14 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
Tapentadol:
Therapeutic: 5-300 ng/mL
N-desmethyltapentadol:
No therapeutic range established
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Tapentadol: 0.5 ng/mL
N-desmethyltapentadol: 0.5 ng/mL
Day(s) Performed
Tuesday