Notes

Antibody results should not be used alone for diagnosis and must be interpreted in light of clinical manifestations and other test results.
SS-B/La antibodies are the serological hallmark of Sjogren’s syndrome, but a small portion of patients remain SS-B/La negative. Although a strong association of neonatal lupus erythematosus (NLE) with anti SS-A/Ro was recognized first, the majority of mothers with babies with NLE are now known to have serum SS-B/La antibodies as well.