Sign in →

Orderable Name SAU Sialic Acid, Free and Total, Random, Urine


Ordering Guidance


This is a recommended screening test for patients suspected to have a diagnosis of free sialic acid storage disease.

Urine oligosaccharides are also recommended for patients with a suspected diagnosis of sialidosis or galactosialidosis.



Necessary Information


Patient's age is required.



Specimen Required


Supplies: Sarstedt 5 mL Aliquot Tube (T914)

Container/Tube: Plastic, 5-mL urine tube

Specimen Volume: 1 mL

Pediatric Volume: 0.5 mL

Collection Instructions: Collect a random urine specimen (early morning preferred).


Forms

1. Biochemical Genetics Patient Information (T602)

2. If not ordering electronically, complete, print, and send a Biochemical Genetics Test Request (T798) with the specimen.

Useful For

Screening for sialic acid disorders

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Specimen Type

Urine

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 90 days
  Frozen  90 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Reference Values

Free Sialic Acid:

≤4 weeks: ≤208 mmol/mol creatinine

5 weeks-12 months: ≤104 mmol/mol creatinine

13 months-18 years: ≤100 mmol/mol creatinine

≥19 years: ≤38 mmol/mol creatinine

 

Total Sialic Acid

≤4 weeks: ≤852 mmol/mol creatinine

5 weeks-12 months: ≤656 mmol/mol creatinine

13 months-18 years: ≤335 mmol/mol creatinine

≥19 years: ≤262 mmol/mol creatinine

 

Total/Free Ratio:

≤4 weeks: 1.94-18.68

5 weeks-12 months: 2.34-13.85

13 months-18 years: 2.63-9.18

≥19 years: 3.35-15.81

 

An interpretive report will also be provided.

Day(s) Performed

Friday

Report Available

5 to 11 days

CPT Code Information

84275