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Orderable Name SALCT Cortisol, Saliva

Additional Codes

CNE Order Code: Cortisol, Saliva

Useful For

Screening for Cushing syndrome

 

Diagnosis of Cushing syndrome in patients presenting with symptoms or signs suggestive of the disease

Specimen Type

Saliva


Necessary Information


Collection time is required.



Specimen Required


If multiple specimens are collected, submit each Salivette under a separate order number.

 

Patient Preparation:

1. Patient should not brush teeth, eat, drink, or take any oral medication for at least 60 minutes before specimen collection.

2. Have patient rinse mouth thoroughly with water for 1-5 seconds. Wait 10 minutes before collecting the specimen to avoid contamination of the saliva by interfering substance.

Supplies: Cortisol, Saliva Collection Kit (T514)

Container/Tube: Sarstedt Salivette

Specimen Volume: 1.5 mL

Collection Instructions:

1. Provide patient with a Saliva Collection Kit (Salivette) containing the Cortisol - Saliva Collection Instructions and ask them to follow the instructions as written.

2. Instruct patient to collect specimen between 11 p.m. and midnight and record collection time on the Cortisol - Saliva Collection Instructions sheet.

3. Instruct patient to return Cortisol - Saliva Collection Instructions with the appropriately labeled Salivette to the laboratory.

Additional Information: Reference values are also available for an 8 a.m. (7 a.m.-9 a.m.) or a 4 p.m. (3 p.m.-5 p.m.) collection, however, the 11 p.m. to midnight collection is preferred.


Specimen Minimum Volume

0.6 mL

Specimen Stability Information

Specimen Type Temperature Time
Saliva Refrigerated (preferred) 28 days
  Frozen  60 days
  Ambient  28 days

Reference Values

7 a.m.-9 a.m.: 100-750 ng/dL

3 p.m.-5 p.m.: <401 ng/dL

11 p.m.-midnight: <100 ng/dL

Day(s) Performed

Monday through Friday

CPT Code Information

82533

Report Available

2 to 5 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-General Request (T239)

-Renal Diagnostics Test Request (T830)