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Orderable Name PINP Procollagen I Intact N-Terminal, Serum

Useful For

Aiding in monitoring antiresorptive and anabolic therapy in patients with osteoporosis

 

An adjunct in the assessment of conditions associated with increased bone turnover, such as Paget disease

 

This test should not be used as a screening test for osteoporosis in the general population.

Specimen Type

Serum


Ordering Guidance


This test should not be requested in patients who have recently received radioisotopes, therapeutically or diagnostically, because of potential assay interference. A recommended time period before collection cannot be provided, as it depends on the isotope administered, the dose given, and the clearance rate in the individual patient. Specimens will be screened for radioactivity prior to analysis. Radioactive specimens received in the laboratory will be held and assayed after the radioactivity has sufficiently decayed. This will result in a test delay.



Specimen Required


Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 0.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.25 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Frozen (preferred) 180 days
  Ambient  7 days
  Refrigerated  7 days

Reference Values

Adult male: 22-87 mcg/L

Adult female premenopausal: 19-83 mcg/L

Adult female postmenopausal: 16-96 mcg/L

Reference values have not been established for patients who are younger than 18 years of age.

Day(s) Performed

Tuesday, Thursday

CPT Code Information

83519

Report Available

2 to 6 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Method Name

Radioimmunoassay (RIA)