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Orderable Name PAI1 Plasminogen Activator Inhibitor Antigen, Plasma


Specimen Required


Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: Plastic vial (polypropylene preferred)

Specimen Volume: 1 mL

Collection Instructions:

1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing.

2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

3. Aliquot plasma into a plastic vial leaving 0.25 mL in the bottom of centrifuged vial.

4. Freeze plasma immediately (no longer than 4 hours after collection) at -20° C or ideally, at or below -40° C.

Specimen Stability Information: Frozen 2 years

Additional Information:

1. Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

2. Each coagulation assay requested should have its own vial.


Useful For

Identification of heredity elevation or deficiency of plasminogen activator inhibitor type 1

 

Determination of risk for veno-occlusive disease associated with bone marrow transplantation

 

Differential diagnosis of impaired fibrinolysis

 

Prognostic marker of occurrence or recurrence of thrombosis

Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Specimen Type

Plasma Na Cit

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

3.0-72.0 ng/mL

Day(s) Performed

Wednesday

Report Available

7 to 12 days

CPT Code Information

85415