Orderable Name NSAI Neurosyphilis IgG, Antibody Index, Spinal Fluid
Specimen Required
Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.
Both spinal fluid (CSF) and serum are required for this test. CSF and serum must be collected within a maximum of 24 hours of each other.
Specimen Type: Spinal fluid
Container/Tube: Sterile vial
Specimen Volume: 2.2 mL
Collection Instructions:
1. The spinal fluid (CSF) specimen must be collected within 24 hours of the serum specimen, preferably at the same time.
2. The CSF aliquot should be from the second, third, or fourth CSF vial collected during the lumbar puncture. Do not submit CSF from the first vial due to the possibility of blood contamination, which will cause specimen rejection.
3. Label vial as spinal fluid or CSF.
4. Band CSF specimen together with the serum sample.
Specimen Type: Serum
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 2.2 mL
Collection Instructions:
1. Within 24 hours of collection of the spinal fluid specimen, a serum specimen must also be collected, preferably at the same time.
2. Centrifuge and aliquot serum into a plastic vial.
3. Label tube as serum.
4. Band serum specimen together with the CSF sample.
Useful For
Aid in the diagnosis of neuroinvasive syphilis as part of a profile
Method Name
Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.
Enzyme-Linked Immunosorbent Assay (ELISA)
Specimen Type
CSFSpecimen Minimum Volume
Spinal fluid: 1.5 mL; Serum: 1.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time |
---|---|---|
CSF | Refrigerated (preferred) | 10 days |
Frozen | 10 days |
Reject Due To
Gross hemolysis | Reject |
Gross lipemia | Reject |
Spinal fluid (CSF) contaminated with blood | Reject |
Reference Values
Only orderable as part of a profile. For more information see NSAIP / Neurosyphilis IgG Antibody Index with VDRL, Serum and Spinal Fluid.
Antibody Index: 0.6-1.2
Reference values apply to all ages.
Day(s) Performed
Monday through Friday
Report Available
2 to 4 daysCPT Code Information
82784 x 2
82040
86780 x 2
82042