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Orderable Name NFLP Neurofilament Light Chain, Plasma


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Lavender top (EDTA)

Acceptable: None

Submission Container/Tube: Plastic screw-top vial

Specimen Volume: 0.6 mL

Collection Information: Centrifuge and aliquot plasma into a plastic vial. Do not submit specimen in original tube.


Useful For

Assessing neuronal damage related to various neurodegenerative diseases

Method Name

Chemiluminescent Enzyme Immunoassay

Specimen Type

EDTA Plasma

Specimen Minimum Volume

0.50 mL

Specimen Stability Information

Specimen Type Temperature Time
EDTA Plasma Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Reference Values

<2.5 years: ≤12.8 pg/mL

2.5 to 4 years: ≤11.8 pg/mL

5 to 9 years: ≤10.4 pg/mL

10 to 14 years: ≤8.8 pg/mL

15 to 19 years: ≤9.2 pg/mL

20 to 24 years: ≤10.4 pg/mL

25 to 29 years: ≤11.9 pg/mL

30 to 34 years: ≤13.5 pg/mL

35 to 39 years: ≤15.3 pg/mL

40 to 44 years: ≤17.3 pg/mL

45 to 49 years: ≤19.7 pg/mL

50 to 54 years: ≤22.4 pg/mL

55 to 59 years: ≤25.4 pg/mL

60 to 64 years: ≤28.8 pg/mL

65 to 69 years: ≤32.7 pg/mL

70 to 74 years: ≤37.1 pg/mL

75 to 79 years: ≤42.1 pg/mL

80 to 84 years: ≤ 47.8 pg/mL

≥85 years: ≤54.3 pg/mL

Day(s) Performed

Monday through Friday

Report Available

1 to 3 days

CPT Code Information

83884