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Orderable Name MPHNU Methylphenidate and Metabolite, Random, Urine

Additional Codes

CNE Order Code: MPHNU


Additional Testing Requirements


If urine creatinine is required or adulteration of the sample is suspected, also order ADULT / Adulterants Survey, Random, Urine. For more information, see ADULT / Adulterants Survey, Random, Urine.



Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Plastic urine container

Submission Container/Tube: Plastic, 5-mL tube

Specimen Volume: 5 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.

Additional Information:

1. No specimen substitutions.

2. STAT requests are not accepted for this test.

3. Submitting less than 1 mL will compromise the ability to perform all necessary testing.


Useful For

Monitoring urine methylphenidate and ritalinic acid concentrations to assess compliance in patients

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Specimen Type

Urine

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 10 days
  Frozen  28 days

Reject Due To

Gross hemolysis OK
Gross icterus OK

Reference Values

Negative

 

Cutoff concentrations by liquid chromatography tandem mass spectrometry:

Methylphenidate: 10 ng/mL

Ritalinic Acid: 50 ng/mL

Day(s) Performed

Monday, Wednesday, Friday

Report Available

2 to 4 days

CPT Code Information

80360

G0480 (if appropriate)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.