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Orderable Name LEVE Levetiracetam, Serum

Additional Codes

CNE Order Code: Keppra

Useful For

Monitoring serum concentration of levetiracetam, particularly in patients with kidney disease

 

Assessing compliance with levetiracetam therapy

 

Assessing potential toxicity of levetiracetam

Specimen Type

Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. For sustained-release formulations only, draw blood a minimum of 12 hours after last dose.

3. Within 2 hours of collection, centrifuge, and aliquot serum into a plastic vial


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

10.0-40.0 mcg/mL

Day(s) Performed

Monday through Sunday

CPT Code Information

80177

Report Available

Same day/1 to 2 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send 1 of the following forms with the specimen:

-Neurology Specialty Testing Client Test Request (T732)

-General Request (T239)

-Therapeutics Test Request (T831)