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HelpOrderable Name FCZAC Certolizumab and Anti-Certolizumab Antibody, DoseASSURE CTZ
Specimen Required
Specimen Type: Serum
Container/Tube: Red or SST
Specimen Volume: 2 mL
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 2 mL of serum frozen in a plastic vial.
To avoid delays in turnaround time when requesting multiple tests, please submit separate frozen specimens for each test requested.
NOTE: High serum biotin concentrations in patients taking biotin supplements may cause an interference in this
assay. Patients may be advised to stop biotin consumption at least 72 hours prior to sample collection.
Useful For
Provides certolizumab drug concentration and anti-certolizumab antibodies in order to optimize treatment and facilitate clinical decision-making.
This assay may be helpful in any patient on certolizumab therapy for Crohn's disease, psoriasis, or other autoimmune condition.
Method Name
Electrochemiluminescence immunoassay (ECLIA); Surface Plasmon Resonance
Specimen Type
SerumSpecimen Minimum Volume
0.60 mL (Note: This volume does not allow for repeat testing.)
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum | Frozen (preferred) | 14 days |
| Refrigerated | 14 days |
Reject Due To
| Gross hemolysis | Gross reject; Mild OK |
| Gross lipemia | Reject |
| Gross icterus | NA |
| Other/Tissue/Swab | Specimens other than indicated |
Reference Values
Certolizumab:
Quantitation Limit: <1.0 ug/mL
Results of 1 ug/mL or higher indicate detection of certolizumab
Anti-Certolizumab Antibody:
Quantitation Limit: <40 ng/mL
Results of 40 ng/mL or higher indicate detection of anti-certolizumab pegol antibodies.
CPT Code Information
80299
82397
Day(s) Performed
Tuesday