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Orderable Name FACYS Acyclovir, Plasma

Additional Codes

EPIC Order Code: LAB3087


Specimen Required


***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***

 

Collection Container/Tube: Lavender top or pink top (EDTA) (Plasma gel/PST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Plasma

Collections Instructions:

1. Centrifuge and aliquot 1 mL of plasma into a plastic vial.

2. Send refrigerated.


Method Name

High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)

Specimen Type

Plasma EDTA

Specimen Minimum Volume

Plasma: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma EDTA Refrigerated (preferred) 30 days
  Frozen  120 days
  Ambient  30 days

Reject Due To

  All specimens will be evaluated by the processing and performing laboratories for test suitability.

Reference Values

Reporting limit determined each analysis.

 

For using Acyclovir:

Usual therapeutic range (vs. Genital Herpes) during chronic oral daily divided dosages of 1200-2400 mg:

Peak: 0.40-2.0 mcg/mL plasma

Trough: 0.14-1.2 mcg/mL plasma

 

For using Valacyclovir as a metabolite:

Mean steady-state (±1 SD) peak plasma levels following a 500 mg twice daily regimen

of Valacyclovir:

2.0-4.0 mcg Acyclovir/mL

Day(s) Performed

Monday through Sunday

Report Available

9 to 11 days

CPT Code Information

80299