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Orderable Name DIA Diazepam and Metabolites, Serum

Additional Codes

CNE Order Code: Diazepam

Useful For

Assessing compliance

 

Monitoring for appropriate therapeutic level

 

Assessing diazepam toxicity

Specimen Type

Serum Red


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Red top (Serum gel/SST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time
Serum Red Refrigerated (preferred) 28 days
  Ambient  28 days
  Frozen  28 days

Reference Values

Therapeutic concentrations

Diazepam: Not established

Diazepam and Nordiazepam: 100-2,500 ng/mL

 

Cutoff concentrations by liquid chromatography tandem mass spectrometry:

Diazepam: 10 ng/mL

Nordiazepam: 10 ng/mL

Oxazepam: 10 ng/mL

Temazepam: 10 ng/mL

Day(s) Performed

Wednesday

CPT Code Information

80299

Report Available

3 to 7 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Forms

If not ordering electronically, complete, print, and send a Therapeutics Test Request (T831) with the specimen.