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Orderable Name COKEP Cocaine and Metabolites, Plasma


Ordering Guidance


Additional drug panels and specific requests are available; call 800-533-1710.



Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube: Gray top (sodium fluoride/potassium oxalate plasma) (PST are not acceptable)

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL Plasma

Collection Instructions:

1. Within 2 hours of collection, centrifuge at 4° C and aliquot plasma into a plastic vial.

2. Freeze the specimen.


Useful For

Confirming drug exposure involving stimulants such as cocaine, benzoylecgonine, m-hydroxy-benzoylecgonine, and cocaethylene

Method Name

Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)

Specimen Type

Plasma

Specimen Minimum Volume

Plasma: 0.5 mL

Specimen Stability Information

Specimen Type Temperature Time
Plasma Frozen (preferred) 28 days
  Refrigerated  6 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus OK

Reference Values

Negative

Positive results are reported with a quantitative result.

 

Cutoff concentrations:

Cocaine: 1.0 ng/mL

Benzoylecgonine: 1.0 ng/mL

Cocaethylene: 1.0 ng/mL

m-Hydroxybenzoylecgonine: 1.0 ng/mL

Day(s) Performed

Thursday

Report Available

3 to 9 days

CPT Code Information

G0480

80353 (if appropriate for select payers)

Clinical Toxicology CPT Code Client Guidance