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Orderable Name C341Q Complement C3 and C4 with Anti-C1q Antibodies, Serum


Specimen Required


Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 1.5 mL

Collection Instructions: Centrifuge and aliquot serum into a plastic vial


Useful For

Evaluating patients with suspected anti-C1q vasculitis

 

Predicting renal involvement in patients with systemic lupus erythematosus

Profile Information

Test ID Reporting Name Available Separately Always Performed
C3 Complement C3, S Yes Yes
C4 Complement C4, S Yes Yes
AC1Q Anti-C1q Antibodies, IgG, S Yes Yes

Method Name

AC1Q: Enzyme-Linked Immunosorbent Assay (ELISA)

C3, C4: Nephelometry

Specimen Type

Serum

Specimen Minimum Volume

0.9 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  21 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Reference Values

C3:

75-175 mg/dL

 

C4:

14-40 mg/dL

 

AC1Q:

<20 U/mL (Negative)

20-39 U/mL (Weak Positive)

40-80 U/mL (Moderate Positive)

>80 U/mL (Strong Positive)

Day(s) Performed

C3, C4: Monday through Friday

AC1Q: Wednesday

Report Available

2 to 8 days

CPT Code Information

86160 x2

83520