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Orderable Name C1INF C1 Esterase Inhibitor, Functional, Serum


Specimen Required


Patient Preparation: Fasting, preferred but not required

Supplies: Sarstedt Aliquot Tube, 5 mL (T914)

Collection Container/Tube:

Preferred: Red top

Acceptable: Serum gel

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Collection Instructions:

1. Immediately after specimen collection, place the tube on wet ice.

2. After sample has clotted on wet ice, centrifuge at 4° C and aliquot serum into a plastic vial.

3. Freeze specimen within 30 minutes of centrifugation. Sample must be placed on dry ice if not frozen immediately.

NOTE: If a refrigerated centrifuge is not available, it is acceptable to use a room temperature centrifuge, provided the specimen is kept on ice before centrifugation and immediately afterward, the serum aliquoted and frozen.


Useful For

Diagnosing hereditary angioedema

 

Monitoring response to C1 esterase inhibitor replacement therapy

Method Name

Enzyme Immunoassay (EIA)

Specimen Type

Serum Red

Specimen Minimum Volume

0.4 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Red Frozen 28 days

Reject Due To

Gross hemolysis OK
Gross lipemia OK
Gross icterus Reject
Heat-inactivated samples Reject

Reference Values

>67% normal (normal)

41-67% normal (equivocal)

<41% normal (abnormal)

Day(s) Performed

Varies

Report Available

3 to 5 days

CPT Code Information

83520