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Orderable Name BAP Bone Alkaline Phosphatase, Serum

Additional Codes

CNE Order Code: Bone Spec Alk Phos

Useful For

Diagnosis and assessment of severity of metabolic bone disease including Paget disease, osteomalacia, and other states of high bone turnover

 

Monitoring efficacy of antiresorptive therapies including postmenopausal osteoporosis treatment

 

The assay is not intended as a screening test for osteoporosis.

 

Measurements of bone turnover markers are not useful for the diagnosis of osteoporosis; diagnosis of osteoporosis should be made based on bone density.

Specimen Type

Serum


Specimen Required


Collection Container/Tube:

Preferred: Serum gel

Acceptable: Red top

Submission Container/Tube: Plastic vial

Specimen Volume: 0.6 mL

Collection Instructions: Centrifuge and aliquot serum into plastic vial.


Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  90 days
  Ambient  7 days

Reference Values

Males

<2 years: 25-221 mcg/L

2-9 years: 27-148 mcg/L

10-13 years: 35-169 mcg/L

14-17 years: 13-111 mcg/L

Adults: ≤20 mcg/L

 

Females

<2 years: 28-187 mcg/L

2-9 years: 31-152 mcg/L

10-13 years: 19-177 mcg/L

14-17 years: 7-41 mcg/L

Adults

Premenopausal: ≤14 mcg/L

Postmenopausal: ≤22 mcg/L

Day(s) Performed

Monday through Saturday

CPT Code Information

84080

Report Available

2 to 3 days

Reject Due To

Gross hemolysis Reject
Gross lipemia OK

Method Name

Immunoenzymatic Assay