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HelpOrderable Name AMIO Amiodarone, Serum
Additional Codes
CNE Order Code: Aminodarone
Useful For
Monitoring amiodarone therapy, especially when amiodarone is coadministered with other drugs that may interact
Evaluating possible amiodarone toxicity
Assessing patient compliance
Specimen Type
Serum RedSpecimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1.5 mL
Collection Instructions:
1. Draw blood no sooner than 12 hours (trough value) after last dose or immediately before next scheduled dose.
2. Centrifuge and aliquot serum into a plastic vial within 2 hours of collection.
Specimen Minimum Volume
0.5 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days | |
| Frozen | 28 days | ||
| Ambient | 24 hours |
Reference Values
AMIODARONE
Trough Value
0.5-2.0 mcg/mL: Therapeutic concentration
>2.5 mcg/mL: Toxic concentration
DESETHYLAMIODARONE
No therapeutic range established for desethylamiodarone; activity and serum concentration are similar to parent drug.
Day(s) Performed
Monday through Friday
CPT Code Information
80151
Report Available
2 to 5 daysReject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Method Name
Liquid Chromatography Mass Spectrometry (LC-MS/MS)
Forms
If not ordering electronically, complete, print, and send a one of the following with the specimen:
-Therapeutics Test Request (T831)
-Cardiovascular Test Request (T724)