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Orderable Name AFP plus Quad Prenatal Request - AFP plus Quad

Important Note

Special requisition must be completed by the physician's office.

Necessary information includes gestational dating, maternal weight, race, date of brith, twinning, smoking and diabetic status

Specimen Type

Blood 

Container Type/Storage

Red top tube 

Minimum Requirement

5-7 mL

Special Handling

2nd trimester serum test including AFP, Estriol, HCG and Inhibin for screening for open neural tube defects, Down Syndrome (Trisomy 21) and Trisomy 18.

May be done between 15 and 22 weeks of gestation.  16 to 18 weeks of gestation is optimal.

Methodology

Immunoassays 

Routine Turnaround Time

2-3 days from receipt

Reference Range

Positive Screen for Open Neural Tubal Defects:

greater than or equal to 2.0 MoM

 

Screen Positive for Down Syndrome greater than or equal to risk of 270

 

Screen Positive for Trisomy 18 greater than or equal to 100

CPT Code

82105

82677

84702

86336